For Friday:
- Bring user numbers and passwords for cluster
- PLEASE, fill out the online class evaluation! (Thank you to the 10 students that did already!)
For Wednesday
- Bring questions for review session
PLEASE, fill out the online class evaluation!
Questions on Exam #8?
Slides for today on HGT detection, supertrees, supermatrix, decomposition approaches.
Goal class 25:
- Know about different approaches to detect HGT events (phylogenetic conflict and using bllast as proxy, gene presence absence, composition based)
- Know about the advantages and disadvantages to use bipartion based analysis to identify phylogenetic conflict.
- Understand why embedded quartets are advantagous.
- Know about the problems associated with shotgun genome sequencing of multicelluar organisms that live with their symbionts and other bacteria - these genome sequences should be considered metagenome sequences.
- Understand that binning based on composition and coverage can help identify genes from the host and differentiate them form bacterial genes. (But might classify genes recently transferred to the host as belonging to bacteria.)
- Understand the demonstration that the UNC tardigrade genome contigs contained many genes not part of the tardigrade genome.
- Know about the difference between supertree and supermatrix approaches, and appreciate the advantages and disadvantages of each approach.