Using the same fitness and frequency for the A1 and A2 allele, explore the impact of population size on drift?
For a larger population size (1000) explore settings that reflect balancing selection.. (w11:.9; w12:1, w22=.95)
What happens, if you decrease the population size?
Using a small initial frequency of allele 1 (e.g. 0.01 with a population of 50) and a large fitness advantage for this allele, perform simulations for 20 populations.
What does this suggest for the effectiveness of natural selection? Does natural selection acting on a single advantageous allele work better in a large population?
Refresh you knowledge of Baysian approaches to phylogenetic inference.
Read the following sections in the Wikipedia entry http://en.wikipedia.org/wiki/Bayesian_inference_in_phylogeny: Intro, Bayesian Inference of Phylogeny, Background and Bases, Pitfalls and controversies, MRBAYES software for Bayesian Inference of Phylogeny)
