MCB 3421 - Fall 2024

Introduction to Molecular Evolution and Bioinformatics

   Instructor: J. Peter Gogarten (OFFICE: BP room 404, gogarten@uconn.edu)

   Teaching Assistant: Daniel Phillips (daniel.s.phillips@uconn.edu)

   The class meets
        MW 11.15AM - 12.05PM    AND     Fridays 10.10.AM-11.40AM or 1.25PM-2.55PM
        Monday's and Wednesday's classes meet in TLS 301. Lecture recordings will become available on huskyCT under Course content.
        Friday's classes will meet in the computer lab located in the TLS 411 .

(for directions follow the above links to the UConn campus map)    

    Reading materials will be posted on huskyCT -- if you cannot get access, send your netID to gogarten@uconn.edu

   We also will have a discussion board on huskyCT. Contributions on the discussion board will count towards your participation grade.

Possibilities to boost your grade:

• Email questions (multiple choice preferred) that could be used for the exams! (counts towards participation).
• Optional Essay Assignment (can take the place of one take-home exam).
• Optional Research Project to Accompany the Course. (Required for honors conversion.)

Exam Questions for Self Study and Correct Answers from Take-Home Exams:
    Check the Take-Home Exams on HuskyCT
    Link to training questions will be posted here.

IMPORTANT DATES:
      10/02   Share you electronic noteboot with the instructors
        10/09   Midterm, TLS301 at 11.15AM -- tentative date
        11/23-12/1 Thanksgiving break 
        12/06   Last Day of Classes
        12/?   Final at ?? in TLS301

  (Please let me know ahead of time, if you have a conflict for conflict for the exam times! See syllabus for exam policy.)

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Running list of Goals, Links to Slides and Study Materials, Assignments
- discuss if things are not clear.
Note: assignments will NOT be copied to huskyCT

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Worksheets for Computerlabs

Computer-lab assignment 01  pdf-version: Intro to Chimera - Binding Pocket Substrate Interactions

   Team based learning 01 (comments in the slides at the end)

Computer-lab assignment 02  pdf-version: Aligning divergent sequences and structures in ChimeraX, morphing subunits in the catalytic cycle

Computer-lab assignment 03  pdf-version: Characterizing intein domains using chimeraX / predict protein structures / protein-dna interactions

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REFRESH THIS PAGE EVERY TIME YOU VISIT IT

Topics - If you have suggestion for additional topics, please let me know,

Syllabus <- (see for grade calculation, exam policy, and penalties for academic misconduct)

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Go here for course pages from previous years

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Send an Email to Peter Gogarten

 

Go the Gogarten-Lab homepage